Virginia Commonwealth University

Make it real.

Featured Researcher

Research Expertise and Focus

Principal investigator on more than 70 research studies funded by both NIH and industry in the areas of depression, anxiety disorders and premenstrual syndrome

Professional Highlights

Memberships and Leadership

  • President, Academy of Women’s Health
  • Chair, Annual Congress on Women’s Health
  • Immediate past president, International Association for Women’s Mental Health
  • Past president, North American Society for Psychosocial Obstetrics and Gynecology
  • Member, American College of Psychiatrists
  • Past member, Virginia Premier Health Plan board

Awards

  • Distinguished Service Award, Psychiatric Society of Virginia
  • Research Scientist Award from the MCV Foundation
  • Best Doctors in America
  • VCU Women in Medicine and Science Professional Achievement Award
  • YWCA Outstanding Woman Award for Health and Science
  • Jewish Women International’s Woman to Watch Award
  • Lilly Welcome Back Award

Editorial

  • Editor-in-Chief, Journal of Women’s Health

Education and Training

  • M.D., Brown University, Providence, R.I.
  • Fellowship in Consultation-Liaison Psychiatry, VCU Medical Center
  • Residency in Psychiatry, VCU Medical Center

 

Selected Publications

Kornstein SG, McIntyre RS, Thase ME, Boucher M. Desvenlafaxine for the treatment of major depressive disorder. Expert Opin Pharmacother. 2014 Jul;15(10):1449-63. doi: 10.1517/14656566.2014.923403. Review. PubMed PMID: 24914479.

Kornstein SG, Clayton A, Bao W, Guico-Pabia CJ. Post hoc analysis of the efficacy and safety of desvenlafaxine 50 mg/day in a randomized, placebo-controlled study of perimenopausal and postmenopausal women with major depressive disorder. Menopause. 2014 Aug;21(8):799-806. doi: 10.1097/GME.0000000000000178. PubMed PMID: 24448103.

Yonkers KA, Kornstein SG, Gueorguieva R, Merry B, Van Steenburgh K, Altemus M. Symptom-Onset Dosing of Sertraline for the Treatment of Premenstrual Dysphoric Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2015 Oct 1;72(10):1037-44. doi: 10.1001/jamapsychiatry.2015.1472. PubMed PMID: 26351969.

Kornstein SG, Keck PE Jr, Herman BK, Puhl RM, Wilfley DE, DiMarco ID. Communication between physicians and patients with suspected or diagnosed binge eating disorder. Postgrad Med. 2015;127(7):661-70. doi: 10.1080/00325481.2015.1084866. PubMed PMID: 26343376.

Clayton AH, Hwang E, Kornstein SG, Tourian KA, Cheng RF, Abraham L, Mele L, Boucher M. Effects of 50 and 100 mg desvenlafaxine versus placebo on sexual function in patients with major depressive disorder: a meta-analysis. Int Clin Psychopharmacol. 2015 Nov;30(6):307-15. doi: 10.1097/YIC.0000000000000094. PubMed PMID: 26230270.

Kornstein SG, Clayton AH, Bao W, Guico-Pabia CJ. A pooled analysis of the efficacy of desvenlafaxine for the treatment of major depressive disorder in perimenopausal and postmenopausal women. J Womens Health (Larchmt). 2015 Apr;24(4):281-90. doi: 10.1089/jwh.2014.4900. PubMed PMID: 25860107.

Haley CL, Sung SC, Rush AJ, Trivedi MH, Wisniewski SR, Luther JF, Kornstein SG. The clinical relevance of self-reported premenstrual worsening of depressive symptoms in the management of depressed outpatients: a STAR*D report. J Womens Health (Larchmt). 2013 Mar;22(3):219-29. PMCID: PMC3634137

Kornstein SG, Toups M, Rush AJ, Wisniewski SR, Harvey AT, Thase ME, Warden D, Fava M, and Trivedi MH. Do menopausal status and use of hormone therapy affect antidepressant treatment response? Findings from the STAR*D study. J Womens Health (Larchmt). 2013 Feb;22(2):121-31. PMCID: PMC3613168

Andrews PW, Kornstein SG, Halberstadt LJ, Gardner CO, Neale MC. Blue again: Perturbational effects of antidepressants suggest monoaminergic homeostasis in major depression. Front Psychol. 2011;2. PMCID: PMC3133866

Adkins DE, Åberg K, McClay JL, Hettema JM, Kornstein SG, Bukszár J, van den Oord EJ. A genomewide association study of citalopram response in major depressive Disorder—A psychometric approach. Biol Psychiatry. 2010 Sep 15;68(6):e25-7. PMCID: PMC2929324

Kornstein SG, Jiang Q, Reddy S, Musgnung JJ, Guico-Pabia CJ. Short-term efficacy and safety of desvenlafaxine in a randomized, placebo-controlled study of perimenopausal and postmenopausal women with major depressive disorder. J Clin Psychiatry. 2010 Aug;71(8):1088-96. PMID:  20797382

Kornstein SG, Young EA, Harvey AT, Wisniewski SR, Barkin JL, Thase ME, Trivedi MH, Nierenberg AA, Rush AJ. The influence of menopausal status and postmenopausal use of hormone therapy on presentation of major depression in women. Menopause. 2010 Jul;17(4):828-39. PMCID: PMC2949279

Warden D, Trivedi MH, Wisniewski SR, Kurian B, Zisook S, Kornstein SG, Friedman ES, Miyahara S, Leuchter AF, Fava M, Rush J. Early adverse events and attrition in SSRI treatment: A suicide assessment methodology study (SAMS) report. J Clin Psychopharmacol. 2010 Jun;30(3):259-66. PMCID: PMC3119579

Kornstein SG, Clayton AH, Soares CN, Padmanabhan SK, Guico-Pabia CJ. Analysis by age and sex of efficacy data from placebo-controlled trials of desvenlafaxine in outpatients with major depressive disorder. J Clin Psychopharmacol. 2010 Jun;30(3):294-9. PMID: 20473066

Kornstein SG, Kocsis JH, Ahmed S, Thase M, Friedman ES, Dunlop BW, Yan B, Pedersen R, Ninan PT, Li T, Keller M. Assessing the efficacy of 2 years of maintenance treatment with venlafaxine extended release 75-225 mg/day in patients with recurrent major depression: a secondary analysis of data from the PREVENT study. Int Clin Psychopharmacol. 2008 Nov;23(6):357-63. PMID: 
18854724

Foster CE, Webster MC, Weissman MM, Pilowsky DJ, Wickramaratne PJ, Talati A, Rush AJ, Hughes CW, Garber J, Malloy E, Cerda G, Kornstein SG, Alpert JE, Wisniewski SR, Trivedi MH, Fava M, King CA. Remission of maternal depression: Relations to family functioning and youth internalizing and externalizing symptoms. J Clin Child Adolesc Psychol. 2008 Oct;37(4):714-24. PMCID: PMC2989174

Foster CE, Webster MC, Weissman MM, Pilowsky DJ, Wickramaratne PJ, Talati A, Rush AJ, Hughes CW, Garber J, Malloy E, Cerda G, Kornstein SG, Alpert JE, Wisniewski SR, Trivedi MH, Fava M, King CA. Remission of maternal depression: relations to family functioning and youth internalizing and externalizing symptoms. J Clin Child Adolesc Psychol. 2008 Oct;37(4):714-24. PMID: 18991123

Kornstein SG, Dunner DL, Meyers AL, Whitmyer VG, Mallinckrodt CH, Wohlreich MM, Detke MJ, Hollandbeck MS, Greist JH. A randomized, double-blind study of increasing or maintaining duloxetine dose in patients without remission of major depressive disorder after initial duloxetine therapy. J Clin Psychiatry. 2008 Sep;69(9):1383-92. PMID:  19193339

Marcus SM, Kerber KB, Rush AJ, Wisniewski SR, Nierenberg A, Balasubramani GK, Ritz L, Kornstein S, Young EA, Trivedi MH. Gender differences in depression symptoms in treatment-seeking adults: STAR*D confirmatory analyses. Compr Psychiatry. 2008 May–Jun;49(3):238-46. PMCID: PMC275928